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Catalytic intramolecular aminoarylation of unactivated alkenes with aryl sulfonamides

Arylethylamines are abundant motifs in myriad natural products and pharmaceuticals, so efficient methods to synthesize them are valuable in drug discovery. In this work, we disclose an intramolecular alkene aminoarylation cascade that exploits the electrophilicity of a nitrogen-centered radical to f...

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Detalles Bibliográficos
Autores principales: Noten, Efrey A., McAtee, Rory C., Stephenson, Corey R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200115/
https://www.ncbi.nlm.nih.gov/pubmed/35774166
http://dx.doi.org/10.1039/d2sc01228f