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Hydroxy-directed fluorination of remote unactivated C(sp(3))–H bonds: a new age of diastereoselective radical fluorination

We report a photochemically induced, hydroxy-directed fluorination that addresses the prevailing challenge of high diastereoselectivity in this burgeoning field. Numerous simple and complex motifs showcase a spectrum of regio- and stereochemical outcomes based on the configuration of the hydroxy gro...

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Detalles Bibliográficos
Autores principales: Harry, Stefan Andrew, Xiang, Michael Richard, Holt, Eric, Zhu, Andrea, Ghorbani, Fereshte, Patel, Dhaval, Lectka, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200124/
https://www.ncbi.nlm.nih.gov/pubmed/35774162
http://dx.doi.org/10.1039/d2sc01907h