Bisulfite-free and single-nucleotide resolution sequencing of DNA epigenetic modification of 5-hydroxymethylcytosine using engineered deaminase

The discovery of 5-hydroxymethylcytosine (5hmC) in mammalian genomes is a landmark in epigenomics study. Similar to 5-methylcytosine (5mC), 5hmC is viewed as a critical epigenetic modification. Deciphering the functions of 5hmC necessitates the location analysis of 5hmC in genomes. Here, we proposed...

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Detalles Bibliográficos
Autores principales: Xie, Neng-Bin, Wang, Min, Ji, Tong-Tong, Guo, Xia, Ding, Jiang-Hui, Yuan, Bi-Feng, Feng, Yu-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200132/
https://www.ncbi.nlm.nih.gov/pubmed/35774177
http://dx.doi.org/10.1039/d2sc01052f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200132/
https://www.ncbi.nlm.nih.gov/pubmed/35774177
http://dx.doi.org/10.1039/d2sc01052f

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