Safety and Antiviral Effects of Nebulized PC786 in a Respiratory Syncytial Virus Challenge Study

BACKGROUND: PC786 is a nebulized nonnucleoside respiratory syncytial virus (RSV) polymerase inhibitor designed to treat RSV, which replicates in the superficial layer of epithelial cells lining the airways. METHODS: Fifty-six healthy volunteers inoculated with RSV-A (Memphis 37b) were randomly dosed...

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Detalles Bibliográficos
Autores principales: DeVincenzo, John, Cass, Lindsey, Murray, Alison, Woodward, Kathy, Meals, Elizabeth, Coates, Matthew, Daly, Leah, Wheeler, Vicky, Mori, Julie, Brindley, Charlie, Davis, Amanda, McCurdy, Meabh, Ito, Kazuhiro, Murray, Bryan, Strong, Pete, Rapeport, Garth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200148/
https://www.ncbi.nlm.nih.gov/pubmed/33216113
http://dx.doi.org/10.1093/infdis/jiaa716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200148/
https://www.ncbi.nlm.nih.gov/pubmed/33216113
http://dx.doi.org/10.1093/infdis/jiaa716

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