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Paradoxically Greater Persistence of HIV RNA-Positive Cells in Lymphoid Tissue When ART Is Initiated in the Earliest Stage of Infection

Starting antiretroviral therapy (ART) in Fiebig 1 acute HIV infection limits the size of viral reservoirs in lymphoid tissues, but does not impact time to virus rebound during a treatment interruption. To better understand why the reduced reservoir size did not increase the time to rebound we measur...

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Detalles Bibliográficos
Autores principales: Kroon, Eugène, Chottanapund, Suthat, Buranapraditkun, Supranee, Sacdalan, Carlo, Colby, Donn J, Chomchey, Nitiya, Prueksakaew, Peeriya, Pinyakorn, Suteeraporn, Trichavaroj, Rapee, Vasan, Sandhya, Manasnayakorn, Sopark, Reilly, Cavan, Helgeson, Erika, Anderson, Jodi, David, Caitlin, Zulk, Jacob, de Souza, Mark, Tovanabutra, Sodsai, Schuetz, Alexandra, Robb, Merlin L, Douek, Daniel C, Phanuphak, Nittaya, Haase, Ashley, Ananworanich, Jintanat, Schacker, Timothy W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200151/
https://www.ncbi.nlm.nih.gov/pubmed/35275599
http://dx.doi.org/10.1093/infdis/jiac089