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Simultaneous prediction of antibody backbone and side-chain conformations with deep learning
Antibody engineering is becoming increasingly popular in medicine for the development of diagnostics and immunotherapies. Antibody function relies largely on the recognition and binding of antigenic epitopes via the loops in the complementarity determining regions. Hence, accurate high-resolution mo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200299/ https://www.ncbi.nlm.nih.gov/pubmed/35704640 http://dx.doi.org/10.1371/journal.pone.0258173 |