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Simultaneous prediction of antibody backbone and side-chain conformations with deep learning

Antibody engineering is becoming increasingly popular in medicine for the development of diagnostics and immunotherapies. Antibody function relies largely on the recognition and binding of antigenic epitopes via the loops in the complementarity determining regions. Hence, accurate high-resolution mo...

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Detalles Bibliográficos
Autores principales: Akpinaroglu, Deniz, Ruffolo, Jeffrey A., Mahajan, Sai Pooja, Gray, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200299/
https://www.ncbi.nlm.nih.gov/pubmed/35704640
http://dx.doi.org/10.1371/journal.pone.0258173

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