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Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with no curative pharmacological treatment. The most used animal model of IPF for anti-fibrotic drug screening is bleomycin (BLM)-induced lung fibrosis. However, several issues have been reported: the balance among disease resolution, an a...

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Detalles Bibliográficos
Autores principales: Khalajzeyqami, Zahra, Grandi, Andrea, Ferrini, Erica, Ravanetti, Francesca, Leo, Ludovica, Mambrini, Martina, Giardino, Luciana, Villetti, Gino, Stellari, Franco Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200302/
https://www.ncbi.nlm.nih.gov/pubmed/35704641
http://dx.doi.org/10.1371/journal.pone.0270005