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Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with no curative pharmacological treatment. The most used animal model of IPF for anti-fibrotic drug screening is bleomycin (BLM)-induced lung fibrosis. However, several issues have been reported: the balance among disease resolution, an a...
Autores principales: | Khalajzeyqami, Zahra, Grandi, Andrea, Ferrini, Erica, Ravanetti, Francesca, Leo, Ludovica, Mambrini, Martina, Giardino, Luciana, Villetti, Gino, Stellari, Franco Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200302/ https://www.ncbi.nlm.nih.gov/pubmed/35704641 http://dx.doi.org/10.1371/journal.pone.0270005 |
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