Induced fit with replica exchange improves protein complex structure prediction

Despite the progress in prediction of protein complexes over the last decade, recent blind protein complex structure prediction challenges revealed limited success rates (less than 20% models with DockQ score > 0.4) on targets that exhibit significant conformational change upon binding. To overco...

Descripción completa

Detalles Bibliográficos
Autores principales: Harmalkar, Ameya, Mahajan, Sai Pooja, Gray, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200320/
https://www.ncbi.nlm.nih.gov/pubmed/35658008
http://dx.doi.org/10.1371/journal.pcbi.1010124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200320/
https://www.ncbi.nlm.nih.gov/pubmed/35658008
http://dx.doi.org/10.1371/journal.pcbi.1010124

Ejemplares similares