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The Caenorhabditis elegans TDRD5/7-like protein, LOTR-1, interacts with the helicase ZNFX-1 to balance epigenetic signals in the germline

LOTUS and Tudor domain containing proteins have critical roles in the germline. Proteins that contain these domains, such as Tejas/Tapas in Drosophila, help localize the Vasa helicase to the germ granules and facilitate piRNA-mediated transposon silencing. The homologous proteins in mammals, TDRD5 a...

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Detalles Bibliográficos
Autores principales: Marnik, Elisabeth A., Almeida, Miguel V., Cipriani, P. Giselle, Chung, George, Caspani, Edoardo, Karaulanov, Emil, Gan, Hin Hark, Zinno, John, Isolehto, Ida J., Kielisch, Fridolin, Butter, Falk, Sharp, Catherine S., Flanagan, Roisin M., Bonnet, Frederic X., Piano, Fabio, Ketting, René F., Gunsalus, Kristin C., Updike, Dustin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200344/
https://www.ncbi.nlm.nih.gov/pubmed/35657999
http://dx.doi.org/10.1371/journal.pgen.1010245