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Cigarette smoke toxin hydroquinone and misfolding pancreatic lipase variant cooperatively promote endoplasmic reticulum stress and cell death

Mutation-induced protein misfolding of pancreatic secretory enzymes and consequent endoplasmic reticulum stress can cause chronic pancreatitis. A recent study revealed that cigarette smoke also increases the risk of the disease through endoplasmic reticulum stress. Here, we investigated the cumulati...

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Detalles Bibliográficos
Autores principales: Kassay, Norbert, Toldi, Vanda, Tőzsér, József, Szabó, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200355/
https://www.ncbi.nlm.nih.gov/pubmed/35704637
http://dx.doi.org/10.1371/journal.pone.0269936