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P(4)O(10)/TfOH mediated domino condensation–cyclization of amines with diacids: a route to indolizidine alkaloids under catalyst- and solvent-free conditions
A domino condensation–cyclization method is developed to synthesize indolizidine alkaloids using a P(4)O(10)/TfOH reagent system without the employment of either a catalyst or solvent. The use of a few aliphatic and aromatic dicarboxylic acids is shown along with various primary amines. This method...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200442/ https://www.ncbi.nlm.nih.gov/pubmed/35765320 http://dx.doi.org/10.1039/d2ra02534e |