Osthole Induces Apoptosis and Caspase-3/GSDME-Dependent Pyroptosis via NQO1-Mediated ROS Generation in HeLa Cells

Osthole is a natural coumarin which has been proved to inhibit growth of cancer cells by inducing cell death, while its mechanism was considered to be just caused by apoptosis. In our study, we found that osthole activated not just apoptosis, but also pyroptosis which is a form of regulated cell dea...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Huangfu, Mengjie, Li, Xiaojuan, Han, Mengjie, Liu, Guoxiang, Yu, Dan, Zhou, Luwei, Dou, Tong, Liu, Yisa, Guan, Xiao, Wei, Riming, Chen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200556/
https://www.ncbi.nlm.nih.gov/pubmed/35720178
http://dx.doi.org/10.1155/2022/8585598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200556/
https://www.ncbi.nlm.nih.gov/pubmed/35720178
http://dx.doi.org/10.1155/2022/8585598

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