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Mechanism of mitoribosomal small subunit biogenesis and preinitiation

Mitoribosomes are essential for the synthesis and maintenance of bioenergetic proteins. Here we use cryo-electron microscopy to determine a series of the small mitoribosomal subunit (SSU) intermediates in complex with auxiliary factors, revealing a sequential assembly mechanism. The methyltransferas...

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Detalles Bibliográficos
Autores principales: Itoh, Yuzuru, Khawaja, Anas, Laptev, Ivan, Cipullo, Miriam, Atanassov, Ilian, Sergiev, Petr, Rorbach, Joanna, Amunts, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200640/
https://www.ncbi.nlm.nih.gov/pubmed/35676484
http://dx.doi.org/10.1038/s41586-022-04795-x