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Modification of ERα by UFM1 Increases Its Stability and Transactivity for Breast Cancer Development

The post-translational modification (e.g., phosphorylation) of estrogen receptor α (ERα) plays a role in controlling the expression and subcellular localization of ERα as well as its sensitivity to hormone response. Here, we show that ERα is also modified by UFM1 and this modification (ufmylation) p...

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Detalles Bibliográficos
Autores principales: Yoo, Hee Min, Park, Jong Ho, Kim, Jae Yeon, Chung, Chin Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200662/
https://www.ncbi.nlm.nih.gov/pubmed/35680375
http://dx.doi.org/10.14348/molcells.2022.0029