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Immuno-reactive cancer organoid model to assess effects of the microbiome on cancer immunotherapy

Immune checkpoint blockade (ICB) therapy has demonstrated good efficacy in many cancer types. In cancers such as non-resectable advanced or metastatic triple-negative breast cancer (TNBC), it has recently been approved as a promising treatment. However, clinical data shows overall response rates (OR...

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Detalles Bibliográficos
Autores principales: Shelkey, Ethan, Oommen, David, Stirling, Elizabeth R., Soto-Pantoja, David R., Cook, Katherine L., Lu, Yong, Votanopoulos, Konstantinos I., Soker, Shay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200712/
https://www.ncbi.nlm.nih.gov/pubmed/35705580
http://dx.doi.org/10.1038/s41598-022-13930-7