Production of high loading insulin nanoparticles suitable for oral delivery by spray drying and freeze drying techniques

Insulin nanoparticles (NPs) with high loading content have found diverse applications in different dosage forms. This work aimed to evaluate the impact of freeze-drying and spray drying process on the structures of insulin-loaded chitosan nanoparticles, with or without mannitol as cryoprotectants. W...

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Detalles Bibliográficos
Autores principales: Guo, Yigong, Baldelli, Alberto, Singh, Anika, Fathordoobady, Farahnaz, Kitts, David, Pratap-Singh, Anubhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200718/
https://www.ncbi.nlm.nih.gov/pubmed/35705561
http://dx.doi.org/10.1038/s41598-022-13092-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200718/
https://www.ncbi.nlm.nih.gov/pubmed/35705561
http://dx.doi.org/10.1038/s41598-022-13092-6

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