Clusterin exacerbates interleukin-1β-induced inflammation via suppressing PI3K/Akt pathway in human fibroblast-like synoviocytes of knee osteoarthritis

This study aimed to examine, a multifaceted chaperon-like protein exerting anti-inflammatory action, clusterin (CLU), mRNA and protein levels in the systemic and local joint environment of knee osteoarthritis (OA) patients and to determine whether CLU inhibited interleukin (IL)-1β-induced inflammati...

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Detalles Bibliográficos
Autores principales: Ungsudechachai, Tachatra, Honsawek, Sittisak, Jittikoon, Jiraphun, Udomsinprasert, Wanvisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200742/
https://www.ncbi.nlm.nih.gov/pubmed/35705674
http://dx.doi.org/10.1038/s41598-022-14295-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200742/
https://www.ncbi.nlm.nih.gov/pubmed/35705674
http://dx.doi.org/10.1038/s41598-022-14295-7

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