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Mitochondrial complex I dysfunction alters the balance of soluble and membrane-bound TNF during chronic experimental colitis

Inflammatory bowel disease (IBD) is a complex, chronic, relapsing and heterogeneous disease induced by environmental, genomic, microbial and immunological factors. MCJ is a mitochondrial protein that regulates the metabolic status of macrophages and their response to translocated bacteria. Previousl...

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Detalles Bibliográficos
Autores principales: Peña-Cearra, Ainize, Pascual-Itoiz, Miguel Angel, Lavín, Jose Luis, Fuertes, Miguel, Martín-Ruiz, Itziar, Castelo, Janire, Palacios, Ainhoa, Barriales, Diego, Fullaondo, Asier, Aransay, Ana M, Rodríguez, Hector, Anguita, Juan, Abecia, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200762/
https://www.ncbi.nlm.nih.gov/pubmed/35705557
http://dx.doi.org/10.1038/s41598-022-13480-y