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Enduring disruption of reward and stress circuit activities by early-life adversity in male rats

In humans, early-life adversity (ELA) such as trauma, poverty, and chaotic environment is linked to increased risk of later-life emotional disorders including depression and substance abuse. These disorders involve underlying disruption of reward circuits and likely vary by sex. Accordingly, we prev...

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Detalles Bibliográficos
Autores principales: Levis, Sophia C., Birnie, Matthew T., Bolton, Jessica L., Perrone, Christina R., Montesinos, Johanna S., Baram, Tallie Z., Mahler, Stephen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200783/
https://www.ncbi.nlm.nih.gov/pubmed/35705547
http://dx.doi.org/10.1038/s41398-022-01988-w