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Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite

Actin polymerization generates forces for cellular processes throughout the eukaryotic kingdom, but our understanding of the ‘ancient’ actin turnover machineries is limited. We show that, despite > 1 billion years of evolution, pathogenic Leishmania major parasite and mammalian actins share the s...

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Detalles Bibliográficos
Autores principales: Kotila, Tommi, Wioland, Hugo, Selvaraj, Muniyandi, Kogan, Konstantin, Antenucci, Lina, Jégou, Antoine, Huiskonen, Juha T., Romet-Lemonne, Guillaume, Lappalainen, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200798/
https://www.ncbi.nlm.nih.gov/pubmed/35705539
http://dx.doi.org/10.1038/s41467-022-31068-y