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The histone H2B Arg95 residue links the pheromone response pathway to rapamycin-induced G(1) arrest in yeast

Rapamycin is an immunosuppressant used for treating many types of diseases such as kidney carcinomas. In yeast, rapamycin inhibits the TORC1 kinase signaling pathway causing rapid alteration in gene expression and ultimately cell cycle arrest in G(1) through mechanisms that are not fully understood....

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Detalles Bibliográficos
Autores principales: Alhaj Sulaiman, Abdallah, Ali, Reem, Aouida, Mustapha, Moovarkumudalvan, Balasubramanian, Ramotar, Dindial
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200821/
https://www.ncbi.nlm.nih.gov/pubmed/35705668
http://dx.doi.org/10.1038/s41598-022-14053-9