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The histone H2B Arg95 residue links the pheromone response pathway to rapamycin-induced G(1) arrest in yeast
Rapamycin is an immunosuppressant used for treating many types of diseases such as kidney carcinomas. In yeast, rapamycin inhibits the TORC1 kinase signaling pathway causing rapid alteration in gene expression and ultimately cell cycle arrest in G(1) through mechanisms that are not fully understood....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200821/ https://www.ncbi.nlm.nih.gov/pubmed/35705668 http://dx.doi.org/10.1038/s41598-022-14053-9 |