TGR5 agonists induce peripheral and central hypersensitivity to bladder distension

The mechanisms underlying chronic bladder conditions such as interstitial cystitis/bladder pain syndrome (IC/BPS) and overactive bladder syndrome (OAB) are incompletely understood. However, targeting specific receptors mediating neuronal sensitivity to specific stimuli is an emerging treatment strat...

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Detalles Bibliográficos
Autores principales: Caldwell, Ashlee, Grundy, Luke, Harrington, Andrea M., Garcia-Caraballo, Sonia, Castro, Joel, Bunnett, Nigel W., Brierley, Stuart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200837/
https://www.ncbi.nlm.nih.gov/pubmed/35705684
http://dx.doi.org/10.1038/s41598-022-14195-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200837/
https://www.ncbi.nlm.nih.gov/pubmed/35705684
http://dx.doi.org/10.1038/s41598-022-14195-w

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