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TGR5 agonists induce peripheral and central hypersensitivity to bladder distension
The mechanisms underlying chronic bladder conditions such as interstitial cystitis/bladder pain syndrome (IC/BPS) and overactive bladder syndrome (OAB) are incompletely understood. However, targeting specific receptors mediating neuronal sensitivity to specific stimuli is an emerging treatment strat...
Autores principales: | Caldwell, Ashlee, Grundy, Luke, Harrington, Andrea M., Garcia-Caraballo, Sonia, Castro, Joel, Bunnett, Nigel W., Brierley, Stuart M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200837/ https://www.ncbi.nlm.nih.gov/pubmed/35705684 http://dx.doi.org/10.1038/s41598-022-14195-w |
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