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Sofosbuvir-based direct-acting antivirals and changes in cholesterol and low density lipoprotein-cholesterol

Worsened lipid profiles were observed in chronic hepatitis C (CHC) patients during direct-acting antivirals (DAAs) treatment, among which combination drugs confounded the effect of individual ingredient on lipid. Tenofovir alafenamide (TAF) also worsened lipid profiles in HIV patients. Structural si...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Kai, Wang, Ying-Wen, Lu, Chia-Ling, Huang, Yi-Hsiang, Hou, Ming-Chih, Chang, Yuh-Lih, Lee, Wei-Ping, Lan, Keng-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200852/
https://www.ncbi.nlm.nih.gov/pubmed/35705594
http://dx.doi.org/10.1038/s41598-022-13657-5