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Selection of start codon during mRNA scanning in eukaryotic translation initiation

Accurate and high-speed scanning and subsequent selection of the correct start codon are important events in protein synthesis. Eukaryotic mRNAs have long 5′ UTRs that are inspected for the presence of a start codon by the ribosomal 48S pre-initiation complex (PIC). However, the conformational state...

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Detalles Bibliográficos
Autores principales: Basu, Ipsita, Gorai, Biswajit, Chandran, Thyageshwar, Maiti, Prabal K., Hussain, Tanweer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200866/
https://www.ncbi.nlm.nih.gov/pubmed/35705698
http://dx.doi.org/10.1038/s42003-022-03534-2