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Selection of start codon during mRNA scanning in eukaryotic translation initiation
Accurate and high-speed scanning and subsequent selection of the correct start codon are important events in protein synthesis. Eukaryotic mRNAs have long 5′ UTRs that are inspected for the presence of a start codon by the ribosomal 48S pre-initiation complex (PIC). However, the conformational state...
Autores principales: | Basu, Ipsita, Gorai, Biswajit, Chandran, Thyageshwar, Maiti, Prabal K., Hussain, Tanweer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200866/ https://www.ncbi.nlm.nih.gov/pubmed/35705698 http://dx.doi.org/10.1038/s42003-022-03534-2 |
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