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Necrosulfonamide Alleviates Acute Brain Injury of Intracerebral Hemorrhage via Inhibiting Inflammation and Necroptosis

OBJECTIVE: Intracerebral hemorrhage (ICH) is the most lethal subtype of stroke, without effective treatment. Necrosulfonamide (NSA), a specific inhibitor for mixed lineage kinase domain-like protein, has been reported to exert neuroprotective effects in neurological diseases by ameliorating neuroinf...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangyu, Zhang, Yan, Wang, Fei, Liu, Yang, Yong, V. Wee, Xue, Mengzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201046/
https://www.ncbi.nlm.nih.gov/pubmed/35721316
http://dx.doi.org/10.3389/fnmol.2022.916249