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The Role of CYP2B6*6 Gene Polymorphisms in 3,5,6-Trichloro-2-pyridinol Levels as a Biomarker of Chlorpyrifos Toxicity Among Indonesian Farmers

OBJECTIVES: One of the most widely used pesticides today is chlorpyrifos (CPF). Cytochrome P450 (CYP)2B6, the most prominent catalyst in CPF bioactivation, is highly polymorphic. The objective of our study was to evaluate the role of CYP2B6*6, which contains both 516G>T and 785A>G polymorphism...

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Detalles Bibliográficos
Autores principales: Liem, Jen Fuk, Suryandari, Dwi A., Malik, Safarina G., Mansyur, Muchtaruddin, Soemarko, Dewi S., Kekalih, Aria, Subekti, Imam, Suyatna, Franciscus D., Pangaribuan, Bertha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Preventive Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201094/
https://www.ncbi.nlm.nih.gov/pubmed/35678002
http://dx.doi.org/10.3961/jpmph.21.641