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Mitochondria-specific peptide amphiphiles induce mitochondrial dysfunction and peripheral T-cell lymphomas (PTCL) damage

BACKGROUND: Peripheral T-cell lymphomas (PTCL) are aggressive lymphomas with poor prognosis, and therefore, there is a pressing need to explore new targets or compounds. Mitochondria may serve as a potential therapeutic target for PTCL. A designed positively-charged segment (pKV) is anchored to the...

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Detalles Bibliográficos
Autores principales: Sun, Qi, Gui, Ailing, Zou, Aihua, Yan, Yichen, Qiu, Shi, Zhu, Shun, Liu, Wen, Zuo, Ji, Zhang, Qunling, Yang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201132/
https://www.ncbi.nlm.nih.gov/pubmed/35722364
http://dx.doi.org/10.21037/atm-22-2233