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Transthyretin-induced increase in circ_0007411 represses neovascularization of human retinal microvascular endothelial cells in hyperglycemia via the miR-548m/PTPN12/SKP1/EGFR pathway

BACKGROUND: To investigate the mechanism of transthyretin (TTR) induced high expression of circ_0007411 and its parent gene, protein tyrosine phosphatase nonreceptor type 12 (PTPN12) in human retinal microvascular endothelial cells (hRECs) cultivated under high glucose condition. METHODS: The levels...

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Detalles Bibliográficos
Autores principales: Hu, Di, Tian, Yikun, Ye, Lu, Xin, Yu, Shao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201143/
https://www.ncbi.nlm.nih.gov/pubmed/35722376
http://dx.doi.org/10.21037/atm-22-1276