G9a promotes inflammation in Streptococcus pneumoniae induced pneumonia mice by stimulating M1 macrophage polarization and H3K9me2 methylation in FOXP1 promoter region

BACKGROUND: Streptococcus pneumoniae has become a leading cause of pneumonia in recent years. Here, we investigated the mechanism of histone methylase G9a in Streptococcus pneumoniae-induced pneumonia (Spn). METHODS: G9a expression in Spn mouse tissue was measured. G9a lentivirus interference vector...

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Detalles Bibliográficos
Autores principales: Li, Yi, Li, Guanhua, Zhang, Li, Li, Yuechuan, Zhao, Zhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201180/
https://www.ncbi.nlm.nih.gov/pubmed/35722379
http://dx.doi.org/10.21037/atm-22-1884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201180/
https://www.ncbi.nlm.nih.gov/pubmed/35722379
http://dx.doi.org/10.21037/atm-22-1884

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