Interference with connective tissue growth factor attenuated fibroblast-to-myofibroblast transition and pulmonary fibrosis

BACKGROUND: The aberrant activation and phenotype shift of resident fibroblasts in lung tissues via fibroblast-to-myofibroblast transition (FMT) is considered a pivotal step in pulmonary fibrogenesis, resulting in excessive extracellular matrix (ECM) production and deposition. However, the molecular...

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Detalles Bibliográficos
Autores principales: Yang, Zhizhou, Wang, Mengmeng, Cao, Liping, Liu, Rui, Ren, Yi, Li, Liang, Zhang, Yuhao, Liu, Chao, Zhang, Wei, Nie, Shinan, Sun, Zhaorui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201195/
https://www.ncbi.nlm.nih.gov/pubmed/35722387
http://dx.doi.org/10.21037/atm-22-1397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201195/
https://www.ncbi.nlm.nih.gov/pubmed/35722387
http://dx.doi.org/10.21037/atm-22-1397

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