Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis

Background and aim: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing irreparable scarring of lung tissue, with most patients succumbing rapidly after diagnosis. The mevalonate pathway, which is involved in the regulation of cell proliferation, survival, and motility, is targ...

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Detalles Bibliográficos
Autores principales: Tanner, Lloyd, Bergwik, Jesper, Single, Andrew B., Bhongir, Ravi K. V., Erjefält, Jonas S., Egesten, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201219/
https://www.ncbi.nlm.nih.gov/pubmed/35721132
http://dx.doi.org/10.3389/fphar.2022.899469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201219/
https://www.ncbi.nlm.nih.gov/pubmed/35721132
http://dx.doi.org/10.3389/fphar.2022.899469

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