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PRMT1 is required for the generation of MHC-associated microglia and remyelination in the central nervous system

Remyelination failure in multiple sclerosis leads to progressive demyelination and inflammation, resulting in neurodegeneration and clinical decline. Microglia are innate immune cells that can acquire a regenerative phenotype to promote remyelination, yet little is known about the regulators control...

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Detalles Bibliográficos
Autores principales: Lee, Jeesan, Villarreal, Oscar David, Wang, Yu Chang, Ragoussis, Jiannis, Rivest, Serge, Gosselin, David, Richard, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201232/
https://www.ncbi.nlm.nih.gov/pubmed/35705491
http://dx.doi.org/10.26508/lsa.202201467