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PRMT1 is required for the generation of MHC-associated microglia and remyelination in the central nervous system
Remyelination failure in multiple sclerosis leads to progressive demyelination and inflammation, resulting in neurodegeneration and clinical decline. Microglia are innate immune cells that can acquire a regenerative phenotype to promote remyelination, yet little is known about the regulators control...
Autores principales: | Lee, Jeesan, Villarreal, Oscar David, Wang, Yu Chang, Ragoussis, Jiannis, Rivest, Serge, Gosselin, David, Richard, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201232/ https://www.ncbi.nlm.nih.gov/pubmed/35705491 http://dx.doi.org/10.26508/lsa.202201467 |
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