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Efficient Detection of the Alternative Spliced Human Proteome Using Translatome Sequencing

Alternative splicing (AS) isoforms create numerous proteoforms, expanding the complexity of the genome. Highly similar sequences, incomplete reference databases and the insufficient sequence coverage of mass spectrometry limit the identification of AS proteoforms. Here, we demonstrated full-length t...

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Detalles Bibliográficos
Autores principales: Wu, Chun, Lu, Xiaolong, Lu, Shaohua, Wang, Hongwei, Li, Dehua, Zhao, Jing, Jin, Jingjie, Sun, Zhenghua, He, Qing-Yu, Chen, Yang, Zhang, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201276/
https://www.ncbi.nlm.nih.gov/pubmed/35720116
http://dx.doi.org/10.3389/fmolb.2022.895746