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Efficient Detection of the Alternative Spliced Human Proteome Using Translatome Sequencing
Alternative splicing (AS) isoforms create numerous proteoforms, expanding the complexity of the genome. Highly similar sequences, incomplete reference databases and the insufficient sequence coverage of mass spectrometry limit the identification of AS proteoforms. Here, we demonstrated full-length t...
Autores principales: | Wu, Chun, Lu, Xiaolong, Lu, Shaohua, Wang, Hongwei, Li, Dehua, Zhao, Jing, Jin, Jingjie, Sun, Zhenghua, He, Qing-Yu, Chen, Yang, Zhang, Gong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201276/ https://www.ncbi.nlm.nih.gov/pubmed/35720116 http://dx.doi.org/10.3389/fmolb.2022.895746 |
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