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Hoxb5 reprogrammes murine multipotent blood progenitors into haematopoietic stem cell‐like cells

OBJECTIVES: The expression of transcription factor Hoxb5 specifically marks the functional haematopoietic stem cells (HSC) in mice. However, our recent work demonstrated that ectopic expression of Hoxb5 exerted little effect on HSC but could convert B‐cell progenitors into functional T cells in vivo...

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Detalles Bibliográficos
Autores principales: Huang, Dehao, Zhao, Qianhao, Zhang, Mengyun, Weng, Qitong, Zhang, Qi, Wang, Kaitao, Dong, Fang, Cheng, Hui, Hu, Fangxiao, Wang, Jinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201374/
https://www.ncbi.nlm.nih.gov/pubmed/35582777
http://dx.doi.org/10.1111/cpr.13235