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Structural Characterization of a Neutralizing Nanobody With Broad Activity Against SARS-CoV-2 Variants

SARS-CoV-2 and its variants, such as the Omicron continue to threaten public health. The virus recognizes the host cell by attaching its Spike (S) receptor-binding domain (RBD) to the host receptor, ACE2. Therefore, RBD is a primary target for neutralizing antibodies and vaccines. Here, we report th...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Zhou, Bingjie, Luo, Zhipu, Lai, Yanling, Huang, Suqiong, Zhou, Yuanze, Li, Yaning, Gautam, Anupriya, Bourgeau, Salome, Wang, Shurui, Bao, Juan, Tan, Jingquan, Lavillette, Dimitri, Li, Dianfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201380/
https://www.ncbi.nlm.nih.gov/pubmed/35722331
http://dx.doi.org/10.3389/fmicb.2022.875840