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Deciphering Sex-Specific Differentiation of Human Fetal Gonads: Insight From Experimental Models

Sex-specific gonadal differentiation is initiated by the expression of SRY in male foetuses. This promotes a signalling pathway directing testicular development, while in female foetuses the absence of SRY and expression of pro-ovarian factors promote ovarian development. Importantly, in addition to...

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Detalles Bibliográficos
Autores principales: Lundgaard Riis, Malene, Jørgensen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201387/
https://www.ncbi.nlm.nih.gov/pubmed/35721511
http://dx.doi.org/10.3389/fcell.2022.902082