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Uric Acid Enhances Neurogenesis in a Parkinsonian Model by Remodeling Mitochondria

BACKGROUND: Adult neurogenesis is the process of generating new neurons to enter neural circuits and differentiate into functional neurons. However, it is significantly reduced in Parkinson’s disease (PD). Uric acid (UA), a natural antioxidant, has neuroprotective properties in patients with PD. Thi...

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Detalles Bibliográficos
Autores principales: Lee, Ji Eun, Shin, Yu Jin, Kim, Yi Seul, Kim, Ha Na, Kim, Dong Yeol, Chung, Seok Jong, Yoo, Han Soo, Shin, Jin Young, Lee, Phil Hyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201452/
https://www.ncbi.nlm.nih.gov/pubmed/35721028
http://dx.doi.org/10.3389/fnagi.2022.851711