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Bafetinib Suppresses the Transcription of PD-L1 Through c-Myc in Lung Cancer

Given the limitations of the existing antibody-based therapies, including immune-related adverse events, poor response rates, and intravenous route of dosing, small molecules inhibitors targeting PD-L1 are highly desirable. By cell-based screening, we found that tyrosine kinase inhibitor Bafetinib d...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Du, Qianqian, Guo, Hongjie, He, Qiaojun, Yang, Bo, Ding, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201485/
https://www.ncbi.nlm.nih.gov/pubmed/35721177
http://dx.doi.org/10.3389/fphar.2022.897747