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Mechanism of CK2 Inhibition by a Ruthenium-Based Polyoxometalate

CK2 is a Ser/Thr protein kinase involved in many cellular processes such as gene expression, cell cycle progression, cell growth and differentiation, embryogenesis, and apoptosis. Aberrantly high CK2 activity is widely documented in cancer, but the enzyme is also involved in several other pathologie...

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Detalles Bibliográficos
Autores principales: Fabbian, Simone, Giachin, Gabriele, Bellanda, Massimo, Borgo, Christian, Ruzzene, Maria, Spuri, Giacomo, Campofelice, Ambra, Veneziano, Laura, Bonchio, Marcella, Carraro, Mauro, Battistutta, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201508/
https://www.ncbi.nlm.nih.gov/pubmed/35720133
http://dx.doi.org/10.3389/fmolb.2022.906390