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Mechanism of CK2 Inhibition by a Ruthenium-Based Polyoxometalate
CK2 is a Ser/Thr protein kinase involved in many cellular processes such as gene expression, cell cycle progression, cell growth and differentiation, embryogenesis, and apoptosis. Aberrantly high CK2 activity is widely documented in cancer, but the enzyme is also involved in several other pathologie...
Autores principales: | Fabbian, Simone, Giachin, Gabriele, Bellanda, Massimo, Borgo, Christian, Ruzzene, Maria, Spuri, Giacomo, Campofelice, Ambra, Veneziano, Laura, Bonchio, Marcella, Carraro, Mauro, Battistutta, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201508/ https://www.ncbi.nlm.nih.gov/pubmed/35720133 http://dx.doi.org/10.3389/fmolb.2022.906390 |
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