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N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression

BACKGROUND/PURPOSE: Mechanical stress plays a vital role in osteogenic differentiation of periodontal ligament stem cells (PDLSCs). Cyclic mechanical stress may up-regulate reactive oxygen species (ROS) level. N-acetylcysteine (NAC) possesses powerful antioxidant capacity. However, it is undefined t...

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Detalles Bibliográficos
Autores principales: Xi, Xun, Li, Zi-Xuan, Zhao, Yi, Liu, Hong, Chen, Shuai, Liu, Dong-Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201541/
https://www.ncbi.nlm.nih.gov/pubmed/35756790
http://dx.doi.org/10.1016/j.jds.2021.10.003