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N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression
BACKGROUND/PURPOSE: Mechanical stress plays a vital role in osteogenic differentiation of periodontal ligament stem cells (PDLSCs). Cyclic mechanical stress may up-regulate reactive oxygen species (ROS) level. N-acetylcysteine (NAC) possesses powerful antioxidant capacity. However, it is undefined t...
Autores principales: | Xi, Xun, Li, Zi-Xuan, Zhao, Yi, Liu, Hong, Chen, Shuai, Liu, Dong-Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Association for Dental Sciences of the Republic of China
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201541/ https://www.ncbi.nlm.nih.gov/pubmed/35756790 http://dx.doi.org/10.1016/j.jds.2021.10.003 |
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