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miR-21 promotes the fibrotic properties in oral mucosa through targeting PDCD4

BACKGROUND/PURPOSE: Oral submucous fibrosis (OSF) has been regarded as a premalignant disorder of oral cancer, and myofibroblasts are the main cells that are responsible for pathological fibrosis. Hence, elucidation of the molecular mechanism underlying myofibroblast activation is important to treat...

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Detalles Bibliográficos
Autores principales: Liao, Yi-Wen, Tsai, Lo-Lin, Lee, Yu-Hsien, Hsieh, Pei-Ling, Yu, Cheng-Chia, Lu, Ming-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201543/
https://www.ncbi.nlm.nih.gov/pubmed/35756803
http://dx.doi.org/10.1016/j.jds.2021.09.004